Demineralized Bone Matrix (DBM) is produced from ground cortical bone and contains osteoinductive proteins. It is intended to be used to fill bone defects and cavities. The increased activity of DBM is assumed to be attributed to the osteoinductive proteins activity. DBM can be used to augment autologous cancellous or corticocancellous grafts. It may also be an alternative for a patient who has no autologous bone available for use as a graft or for a patient who does not wish to undergo an extensive open procedure or for whom open procedure carries a very high risk.